| Show | Prime Minister's Questions |
| Mike Myers | ... | John Major |
| Will Ferrell | ... | Michael Shersby |
| Ana Gasteyer | ... | announcer Voice |
| Darrell Hammond | ... | Clive Budgen |
| Mark McKinney | ... | Simon Coombs |
| Tim Meadows | ... | Roderick Richards |
| Andy Murphy | ... | panelist |
| Colin Quinn | ... | Paddy Donohoe |
| Molly Shannon | ... | Betty Boothroyd |