| Show |
| Sofia Vergara | ... | Yolanda Melinda Netoyez |
| Niall Horan | ... | Dick |
| Zayn Malik | ... | Miguelito |
| Liam Payne | ... | Martito |
| Harry Styles | ... | Carlito |
| Louis Tomlinson | ... | Pepito |
| Fred Armisen | ... | Manuel Ortiz |
| Bill Hader | ... | Junior Netoyez Jr. |
| Bill Hader | ... | announcer Voice |
| Taran Killam | ... | Dr. Osny |
| Kenan Thompson | ... | guard |
| Kristen Wiig | ... | Florida |