| Show |
| Bradley Cooper | ... | Craig Craigstofferson |
| Taylor Swift | ... | Allison |
| Kerry Washington | ... | Dr. Juliana Richards |
| Betty White | ... | Aunt Lana |
| Fred Armisen | ... | Stuart |
| Vanessa Bayer | ... | Rosa |
| Bill Hader | ... | Devin |
| Bill Hader | ... | announcer Voice |
| Taran Killam | ... | Todd Garnes |
| Laraine Newman | ... | Karina's mother |
| David Spade | ... | Total Bastard Airlines steward |
| Cecily Strong | ... | flight attendant |
| Kenan Thompson | ... | Trey |
| Kristen Wiig | ... | Karina |