| Sketch | Medical Breakthrough |
| Chadwick Boseman | ... | Dr. Connelly |
| Aidy Bryant | ... | Dr. Karen Price |
| Kate McKinnon | ... | Sandra Madsen |
| Cecily Strong | ... | reporter |
| Mikey Day | ... | Dan Madsen |
| Heidi Gardner | ... | reporter |
| Alex Moffat | ... | reporter |
| Chris Redd | ... | reporter |
| Takako Haywood | ... | reporter |
| Zana Markelson | ... | reporter |
| Guy Veryzer | ... | reporter |