| Cold Opening | Equality Town Hall |
| Woody Harrelson | ... | Joe Biden Live |
| Lin-Manuel Miranda | ... | Julián Castro Live |
| Billy Porter | Live | |
| Beck Bennett | ... | audience member |
| Aidy Bryant | ... | audience member |
| Colin Jost | ... | Pete Buttigieg Live |
| Kate McKinnon | ... | Elizabeth Warren Live |
| Alex Moffat | ... | Anderson Cooper Live |
| Kyle Mooney | ... | Daniel |
| Chris Redd | ... | Cory Booker Live |
| Melissa Villaseñor | ... | audience member |
| Bowen Yang | ... | audience member |
| Steve Higgins | ... | announcer Voice |
| Zana Markelson | ... | audience member |