| Cold Opening | White House Press Conference |
| John Mulaney | ... | Joe Biden |
| Fred Armisen | ... | Mike Bloomberg#8 Live |
| Larry David | ... | Bernie Sanders#14 Live |
| Rachel Dratch | ... | Amy Klobuchar#5 Live |
| Beck Bennett | ... | Mike Pence#20 Live |
| Colin Jost | ... | Pete Buttigieg#6 Live |
| Kate McKinnon | ... | Elizabeth Warren#11 Live |
| Kenan Thompson | ... | Ben Carson#3 |
| Anthony Rocco Cavaleri | ... | reporter |
| Rebecca Merle | ... | reporter |