| Show | Eye On Pittsburgh |
| Chris Rock | ... | Dr. Kevin Joseph |
| Beck Bennett | ... | Mike Rodick |
| Pete Davidson | ... | doctor |
| Mikey Day | ... | Dylan Bertram |
| Heidi Gardner | ... | Ashley Spitzer-Swallows |
| Ego Nwodim | ... | Edith Puthie#1 |
| Kenan Thompson | ... | Jeffrey B. Epstein |
| Lauren Holt | ... | Irma Gerd |
| Steve Higgins | ... | announcer Voice |
| Cristina Duarte | ... | nurse |