March 12, 2022#1
| Cold Opening | White House TikTok Meeting |
| Aidy Bryant | ... | creator Live |
| Andrew Dismukes | ... | creator Live |
| Chloe Fineman | ... | AnnaLynne McCord Live |
| James Austin Johnson | ... | Joe Biden Live |
| Kate McKinnon | ... | Jen Psaki Live |
| Chris Redd | ... | Jason Derulo Live |
| Kenan Thompson | ... | Charles F. D'Amelio |
| Melissa Villaseñor | ... | creator Live |
| Bowen Yang | ... | Mr Uekusa Live |
| Steve Higgins | ... | announcer Voice |