May 14, 2022#1
| Cold Opening | MSNBC Special Report |
| Aidy Bryant | ... | Camille Vasquez Live |
| Heidi Gardner | ... | Elaine Bredehoft Live |
| Kate McKinnon | ... | Nicole Wallace |
| Kyle Mooney | ... | Johnny Depp Live |
| Ego Nwodim | ... | Tasha Live |
| Chris Redd | ... | Jamal Live |
| Cecily Strong | ... | Penney Azcarate Live |
| Kenan Thompson | ... | Leonard Green Live |
| Melissa Villaseñor | ... | Sofia Live |
| Steve Higgins | ... | announcer Voice |