October 1, 2022#1
| Cold Opening | ManningCast |
| Miles Teller | ... | Peyton Manning Live |
| Jon Hamm | Live | |
| Shaun White | Live | |
| Mikey Day | ... | Donald Trump Jr. Live |
| Andrew Dismukes | ... | Eli Manning Live |
| Chloe Fineman | ... | Jenna Ellis Live |
| Heidi Gardner | ... | Kristi Noem Live |
| Marcello Hernández | Live | |
| James Austin Johnson | ... | Donald Trump Live |
| Molly Kearney | Live | |
| Michael Longfellow | ... | aide Live |
| Sarah Sherman | Live | |
| Devon Walker | ... | Tariq Tull Live |
| Bowen Yang | ... | Xi Jinping Live |