| Sketch | Invasion of the Brain Snatchers |
| Strother Martin | ... | Lucius Kilroy |
| Jane Curtin | ... | volunteer |
| Garrett Morris | ... | L.C. |
| Bill Murray | ... | Bob |
| Laraine Newman | ... | Sue |
| Gilda Radner | ... | Marcia |
| Harry Shearer | ... | Steve |
| Tom Davis | ... | Carl |
| Brian Doyle-Murray | ... | volunteer |
| Paul Shaffer | ... | volunteer |
| Anne Beatts | ... | volunteer |
| Tom Gammill | ... | volunteer |
| Sarah Paley | ... | volunteer |
| Don Pardo | ... | news anchor Voice |
| Max Pross | ... | volunteer |
| Andy Murphy | ... | volunteer |