| Show | Pee-Wee's Thanksgiving Special |
| Pee-Wee Herman | ||
| Joan Cusack | ... | Brooke Shields |
| Robert Downey Jr. | ... | John Oates |
| Anthony Michael Hall | ... | Daryl Hall |
| Terry Sweeney | ... | Diana Ross |
| Danitra Vance | ... | Cicely Tyson |
| Lanier Laney | ... | pilgrim |
| Don Pardo | ... | announcer Voice |
⁕Robin Duke can be seen in the audience during the Diana Ross performance.