| Cold Opening | Democratic Debate |
| Fred Armisen | ... | Mike Bloomberg#7 Live |
| Alec Baldwin | ... | Donald Trump#45 Live |
| Larry David | ... | Bernie Sanders#12 Live |
| Rachel Dratch | ... | Amy Klobuchar#3 Live |
| Maya Rudolph | ... | Kamala Harris#3 Live |
| Jason Sudeikis | ... | Joe Biden#25 Live |
| Heidi Gardner | ... | Judy Woodruff#1 Live |
| Colin Jost | ... | Pete Buttigieg#4 Live |
| Kate McKinnon | ... | Elizabeth Warren#9 |
| Kate McKinnon | ... | Nancy Pelosi#6 Live |
| Cecily Strong | ... | Tulsi Gabbard#2 |
| Bowen Yang | ... | Andrew Yang#3 Live |
| Steve Higgins | ... | announcer Voice |